Composition
Hydroxyzine (Hydrochloride or Pamoate, depending on the formulation)
Hydroxyzine is a first-generation antihistamine with anxiolytic, sedative, and antiemetic properties.
Uses
- Allergic Reactions:
- Relief from itching, hives, and other symptoms caused by allergies.
- Used for conditions like urticaria, dermatitis, and allergic rhinitis.
- Anxiety and Tension:
- Provides short-term relief from anxiety and tension associated with psychoneurotic disorders.
- Acts as a sedative in preoperative and postoperative situations.
- Sleep Disorders:
- Helps manage insomnia and sleep disturbances due to its sedative properties.
- Nausea and Vomiting:
- Effective in controlling nausea and vomiting, especially in post-surgical and motion sickness scenarios.
- Other Uses:
- Management of pruritus in conditions like eczema.
- Adjunctive therapy in alcohol withdrawal.
Indications
- Management of allergic conditions with itching and inflammation.
- Short-term treatment of anxiety and agitation.
- Sedation before and after surgical procedures.
- Control of nausea, vomiting, and motion sickness.
Benefits
- Fast-acting relief from allergic symptoms.
- Dual action as an anxiolytic and sedative.
- Helps manage sleep disturbances associated with anxiety or allergies.
Precautions
- Contraindications: Not recommended for individuals with prolonged QT interval, pregnancy (especially early stages), or known hypersensitivity to hydroxyzine.
- Side Effects: May cause drowsiness, dry mouth, dizziness, or blurred vision.
- Caution: Use cautiously in elderly patients, as it may cause sedation or confusion. Avoid alcohol during treatment.
Dosage and Administration
Hydroxyzine 6 mg/ml (Oral Solution):
- Adults: Typically, 25–50 mg/day in divided doses.
- Children: 0.6 mg/kg/day in divided doses, based on the severity of the condition.
Hydroxyzine 100 mg/5 ml (Oral Syrup):
- Adults: 10–25 mg, 3–4 times daily, adjusted based on response.
- Children: Dose determined by weight and age, under medical supervision.
Hydroxyzine 25 mg (Tablets):
- Adults: 25–100 mg/day in divided doses, depending on the condition.
- Children: 10–25 mg/day, under supervision.
Important Notes
- Avoid driving or operating heavy machinery while on Hydroxyzine due to drowsiness.
- Not recommended for long-term use as an anxiolytic.
- Regular medical monitoring is advised for individuals with a history of cardiovascular disorders.
Hydroxyzine is a versatile medication offering effective relief from allergies, anxiety, and nausea. Always use under the supervision of a healthcare professional.
